Record:
This week: SU – 43-18; ATS – 36-22-1; O/U – 31-27-1
Overall: SU – 436-135; ATS – 246-247-5; O/U – 232-258-8
(Results in parentheses)
| Saturday, November 6 | |||
| Matchup | Time | TV | Prediction |
| Army (+2.5) at Air Force (O/U 37.5) | 11:30 a.m. | CBS | Air Force, 24-17 (Army, 21-14 OT) |
| #21 Pittsburgh (-21) at Duke (O/U 64.5) | Noon | ACCN | Pittsburgh, 45-14 (Pittsburgh, 54-29) |
| #9 Wake Forest (+2.5) at North Carolina (O/U 77) | Noon | ABC | Wake Forest, 45-35 (North Carolina, 58-55) |
| Kansas State (-24) at Kansas (O/U 56) | Noon | FS1 | Kansas State, 38-20 (Kansas State, 35-10) |
| #4 Ohio State (-14.5) at Nebraska (O/U 67.5) | Noon | FOX | Ohio State, 34-21 (Ohio State, 26-17) |
| Illinois (+14.5) at Minnesota (O/U 44) | Noon | ESPN2 | Minnesota, 24-14 (Illinois, 14-6) |
| Missouri (-39.5) at #1 Georgia (O/U 59.5) | Noon | ESPN | Georgia, 45-7 (Georgia, 43-6) |
| Liberty (+9.5) at #15 Ole Miss (O/U 67) | Noon | SECN | Ole Miss, 41-17 (Ole Miss, 27-14) |
| SMU (-4.5) at Memphis (O/U 70.5) | Noon | ESPNU | SMU, 41-24 (Memphis, 28-25) |
| Louisiana Tech (+13.5) at UAB (O/U 49.5) | Noon | CBSSN | UAB, 31-13 (UAB, 52-38) |
| Georgia Tech (+10.5) at Miami (Fla.) (O/U 63.5) | 12:30 p.m. | CSS | Miami, 38-30 (Miami, 33-30) |
| Appalachian State (-21) at Arkansas State (O/U 68.5) | 2 p.m. | ESPN+ | Appalachian State, 45-21 (Appalachian State, 48-14) |
| California (-9) at Arizona (O/U 49.5) | 3 p.m. | P12N | California, 27-17 (Arizona, 10-3) |
| Temple (+15.5) at East Carolina (O/U 53.5) | 3 p.m. | ESPN+ | East Carolina, 38-17 (East Carolina, 45-3) |
| North Texas (-4.5) at Southern Miss (O/U 49) | 3 p.m. | ESPN+ | North Texas, 27-20 (North Texas, 38-14) |
| Louisiana-Monroe (+3.5) at Texas State (O/U 58.5) | 3 p.m. | ESPN+ | Louisiana-Monroe, 31-27 (Texas State, 27-19) |
| #24 Penn State (-10) at Maryland (O/U 56) | 3:30 p.m. | FS1 | Penn State, 31-17 (Penn State, 31-14) |
| #22 Wisconsin (-13) at Rutgers (O/U 38) | 3:30 p.m. | BTN | Wisconsin, 28-7 (Wisconsin, 52-3) |
| #12 Oklahoma State (-3.5) at West Virginia (O/U 49) | 3:30 p.m. | ESPN | Oklahoma State, 31-27 (Oklahoma State, 24-3) |
| #7 Michigan State (-3) at Purdue (O/U 53) | 3:30 p.m. | ABC | Michigan State, 23-17 (Purdue, 40-20) |
| #13 Auburn (+4.5) at #11 Texas A&M (O/U 49.5) | 3:30 p.m. | CBS | Texas A&M, 35-30 (Texas A&M, 20-3) |
| #14 Baylor (-7) at TCU (O/U 58) | 3:30 p.m. | FOX | Baylor, 34-20 (TCU, 30-28) |
| Idaho State (NL) at #17 BYU | 3:30 p.m. | ESPN3 | BYU, 63-7 (BYU, 59-14) |
| Colorado State (-3.5) at Wyoming (O/U 41) | 3:30 p.m. | CBSSN | Colorado State, 24-20 (Wyoming, 31-17) |
| Tulsa (+22.5) at #2 Cincinnati (O/U 55.5) | 3:30 p.m. | ESPN2 | Cincinnati, 34-17 (Cincinnati, 28-20) |
| Navy (+21) at #6 Notre Dame (O/U 47.5) | 3:30 p.m. | NBC | Notre Dame, 24-17 (Notre Dame, 34-6) |
| Rhode Island (NL) at UMass | 3:30 p.m. | FLOF | UMass, 31-28 (Rhode Island, 35-22) |
| South Alabama (+4) at Troy (O/U 47.5) | 3:30 p.m. | ESPN+ | Troy, 31-28 (Troy, 31-24) |
| Middle Tennessee (+17.5) at Western Kentucky (O/U 67) | 3:30 p.m. | STAD | Western Kentucky, 41-21 (Western Kentucky, 48-21) |
| Rice (+6.5) at Charlotte (O/U 52.5) | 3:30 p.m. | ESPN+ | Charlotte, 27-24 (Charlotte, 31-24) |
| N.C. State (-2.5) at Florida State (O/U 55.5) | 4 p.m. | ACCN | N.C. State, 34-27 (N.C. State, 28-14) |
| Utah State (-18.5) at New Mexico State (O/U 72) | 4 p.m. | FLOF | Utah State, 47-27 (Utah State, 35-13) |
| Mississippi State (+4.5) at Arkansas (O/U 54) | 4 p.m. | SECN | Mississippi State, 34-30 (Arkansas, 31-28) |
| Tulane (+13) at UCF (O/U 59) | 4 p.m. | ESPNU | UCF, 41-17 (UCF, 14-10) |
| #20 Coastal Carolina (-19.5) at Georgia Southern (O/U 60.5) | 6 p.m. | ESPN+ | Coastal Carolina, 45-21 (Coastal Carolina, 28-8) |
| Marshall (-1) at FAU (O/U 57.5) | 6 p.m. | FCBK | FAU, 30-27 (Marshall, 28-13) |
| Oregon State (-11.5) at Colorado (O/U 55) | 7 p.m. | P12N | Colorado, 31-17 (Colorado, 37-34) |
| #25 Iowa (-12) at Northwestern (O/U 40.5) | 7 p.m. | BTN | Iowa, 27-14 (Iowa, 17-12) |
| Tennessee (-1) at #23 Kentucky (O/U 56.5) | 7 p.m. | ESPN2 | Kentucky, 27-24 (Tennessee, 45-42_ |
| LSU (+28.5) at #5 Alabama (O/U 66.5) | 7 p.m. | ESPN | Alabama, 48-17 (Alabama, 20-14) |
| Boise State (+5) at Fresno State (O/U 61) | 7 p.m. | CBSSN | Fresno State, 31-24 (Boise State, 40-14) |
| UNLV (+1.5) at New Mexico (O/U 45) | 7 p.m. | STAD | UNLV, 27-20 (UNLV, 31-17) |
| Old Dominion (-3) at FIU (O/U 51) | 7 p.m. | ESPN3 | Old Dominion, 31-27 (Old Dominion, 47-24) |
| Texas (+6.5) at Iowa State (O/U 59.5) | 7:30 p.m. | FS1 | Iowa State, 31-24 (Iowa State, 30-7) |
| Indiana (+20.5) at #10 Michigan (O/U 51) | 7:30 p.m. | FOX | Michigan, 38-14 (Michigan, 29-7) |
| #8 Oregon (-7) at Washington (O/U 49.5) | 7:30 p.m. | ABC | Oregon, 28-20 (Oregon, 26-16) |
| Florida (-20) at South Carolina (O/U 52) | 7:30 p.m. | SECN | Florida, 31-17 (South Carolina, 40-17) |
| Clemson (-4) at Louisville (O/U 46.5) | 7:30 p.m. | ACCN | Louisville, 24-20 (Clemson, 30-24) |
| #16 Houston (-13) at South Florida (O/U 53) | 7:30 p.m. | ESPNU | Houston, 41-17 (Houston, 54-42) |
| San Jose State (+10.5) at Nevada (O/U 55.5) | 10 p.m. | FS2 | Nevada, 41-28 (Nevada, 27-24) |
| #18 UTSA (-11.5) at UTEP (O/U 53) | 10:15 p.m. | ESPN2 | UTSA, 34-30 (UTSA, 44-23) |
| USC (+9) at Arizona State (O/U 61) | 10:30 p.m. | ESPN | Arizona State, 27-20 (Arizona State, 31-16) |
| San Diego State (-7) at Hawaii (O/U 45) | 11 p.m. | FS1 | San Diego State, 34-21 (San Diego State, 17-10) |
| Friday, November 5 | |||
| Matchup | Time | TV | Prediction |
| Virginia Tech (-1) at Boston College (O/U 50.5) | 7:30 p.m. | ESPN2 | Boston College, 23-17 (Boston College, 17-3) |
| Utah (-10) at Stanford (O/U 52.5) | 10:30 p.m. | FS1 | Utah, 31-20 (Utah, 52-7) |
| Thursday, November 4 | |||
| Matchup | Time | TV | Prediction |
| Georgia State (+13.5) at Louisiana (O.U 53) | 7:30 p.m. | ESPN | Louisiana, 34-21 (Louisiana, 21-17) |
| Wednesday, November 3 | |||
| Matchup | Time | TV | Prediction |
| Northern Illinois (+4) at Kent State (O/U 72) | 7 p.m. | ESPN2 | Kent State, 35-30 (Kent State, 52-47) |
| Central Michigan (+9) at Western Michigan (O/U 65.5) | 7 p.m. | ESPNU | Western Michigan, 34-31 (Central Michigan, 42-30) |
| Tuesday, November 2 | |||
| Matchup | Time | TV | Prediction |
| Ball State (-20.5) at Akron (O/U 58) | 7 p.m. | CBSSN | Ball State, 35-21 (Ball State, 31-25) |
| Miami (Ohio) (-7) at Ohio (O/U 54.5) | 7:30 p.m. | ESPNU | Miami, 30-24 (Akron, 35-33) |
| Eastern Michigan (+10) at Toledo (O/U 55) | 7:30 p.m. | ESPN2 | Toledo, 48-40 (Eastern Michigan, 52-49) |
