Record:
This week: SU – 5-0; ATS – 3-2-0; O/U – 4-1-0
Overall: SU – 247-61; ATS – 114-121-4; O/U – 110-126-4
(Results in parentheses)
| Saturday, October 9 | |||
| Matchup | Time | TV | Prediction |
| #19 Michigan State (-5.5) at Rutgers (O/U 50 | Noon | BTN | Michigan State, 31-23 |
| Maryland (+21) at #6 Ohio State (O/U 71) | Noon | FOX | Ohio State, 48-21 |
| Akron (+14.5) at Bowling Green (O/U 46) | Noon | ESPN+ | Bowling Green, 27-17 |
| Northern Illinois (+12.5) at Toledo (O/U 51.5) | Noon | CBSSN | Toledo, 31-17 |
| Vanderbilt (+38.5) at #24 Florida (O/U 59.5) | Noon | SECN | Florida, 45-14 |
| South Carolina (+10.5) at Tennessee (O/U 57) | Noon | ESPN2 | Tennessee, 35-23 |
| #18 Arkansas (+5.5) at Ole Miss (O/U 66.5) | Noon | ESPN | Ole Miss, 38-31 |
| West Virginia (+3) at #25 Baylor (O/U 44.5) | Noon | FS1 | Baylor, 27-21 |
| #4 Oklahoma (-3.5) vs. #12 Texas (O/U 63.5) (at Dallas) | Noon | ABC | Texas, 35-31 |
| Georgia Tech (-3.5) at Duke (O/U 60.5) | Noon | CSS | Georgia Tech, 35-30 |
| Old Dominion (+21) at Marshall (O/U 66) | 2 p.m. | FCBK | Marshall, 49-21 |
| Virginia (+2.5) at Louisville (O/U 69.5) | 3 p.m. | ACCN | Louisville, 41-34 |
| Florida State (+17.5) at North Carolina (O/U 64.5) | 3:30 p.m. | ESPN | North Carolina, 45-24 |
| #21 Wake Forest (-6) at Syracuse (O/U 57) | 3:30 p.m. | ESPN2 | Wake Forest, 31-21 |
| Wisconsin (-10) at Illinois (O/U 42) | 3:30 p.m. | BTN | Wisconsin, 27-14 |
| Miami (Ohio) (-1.5) at Eastern Michigan (O/U 59) | 3:30 p.m. | ESPN+ | Miami, 31-27 |
| Central Michigan (-5) at Ohio (O/U 57) | 3:30 p.m. | ESPN+ | Central Michigan, 27-24 |
| Ball State (+11) at Western Michigan (O/U 57.5) | 3:30 p.m. | ESPNU | Western Michigan, 31-23 |
| #2 Georgia (-15.5) at #13 Auburn (O/U 46.5) | 3:30 p.m. | CBS | Georgia, 34-14 |
| Boise State (+6) at #9 BYU (O/U 56.5) | 3:30 p.m. | ABC | BYU, 31-21 |
| San Jose State (+2.5) at Colorado State (O/U 45) | 3:30 p.m. | FS1 | San Jose State, 24-20 |
| SMU (-13.5) at Navy (O/U 55.5) | 3:30 p.m. | CBSSN | SMU, 41-21 |
| UConn (-3.5) at UMass (O/U 57) | 3:30 p.m. | FLOF | UConn, 33-27 |
| FAU (+4.5) at UAB (O/U 48.5) | 3:30 p.m. | STAD | FAU, 26-21 |
| Middle Tennessee (+19.5) at Liberty (O/U 58) | 3:30 p.m. | ESPN3 | Liberty, 41-17 |
| North Texas (+19) at Missouri (O/U 69) | 4 p.m. | SECN | Missouri, 45-10 |
| #7 Penn State (+1.5) at #5 Iowa (O/U 40.5) | 4 p.m. | FOX | Iowa, 24-17 |
| Oregon State (-3.5) at Washington State (O/U 59) | 4 p.m. | P12N | Oregon State, 31-24 |
| East Carolina (+10) at UCF (O/U 67.5) | 6 p.m. | ESPN+ | TBD |
| Buffalo (+5.5) at Kent State (O/U 65) | 7 p.m. | ESPNU | TBD |
| TCU (-1.5) at Texas Tech (O/U 61) | 7 p.m. | ESPN | TBD |
| Wyoming (+6) at Air Force (O/U 47) | 7 p.m. | CBSSN | TBD |
| UTEP (-2) at Southern Miss (O/U 44.5) | 7 p.m. | ESPN3 | TBD |
| South Alabama (-3.5) at Texas State (O/U 52.5) | 7 p.m. | ESPN+ | TBD |
| Georgia Southern (+5.5) at Troy (O/U 50) | 7 p.m. | ESPN+ | TBD |
| UTSA (+3.5) at Western Kentucky (O/U 69.5) | 7 p.m. | STAD | TBD |
| #10 Notre Dame (Even) at Virginia Tech (O/U 47) | 7:30 p.m. | ACCN | TBD |
| #8 Michigan (-3.5) at Nebraska (O/U 50.5) | 7:30 p.m. | ABC | TBD |
| LSU (+3) at #16 Kentucky (O/U 50) | 7:30 p.m. | SECN | TBD |
| Utah (+3) at USC (O/U 52.5) | 8 p.m. | FOX | TBD |
| #1 Alabama (-17.5) at Texas A&M (O/U 51.5) | 8 p.m. | CBS | TBD |
| Georgia State (-16) at Louisiana-Monroe (O/U 51) | 8 p.m. | ESPN3 | TBD |
| New Mexico (+19.5) at San Diego State (O/U 42) | 9 p.m. | FS1 | TBD |
| Memphis (+3) at Tulsa (O/U 61) | 9 p.m. | ESPN2 | TBD |
| New Mexico State (+31) at Nevada (O/U 62.5) | 10:30 p.m. | CBSSN | TBD |
| UCLA (-16) at Arizona (O/U 61) | 10:30 p.m. | ESPN | TBD |
| Friday, October 8 | |||
| Matchup | Time | TV | Prediction |
| Temple (+30) at #3 Cincinnati (O/U 53) | 7 p.m. | ESPN | Cincinnati, 45-14 (Cincinnati, 52-3) |
| Charlotte (-3.5) at FIU (O/U 61.5) | 7 p.m. | CBSSN | Charlotte, 34-27 (Charlotte, 45-33) |
| Stanford (+13.5) at #22 Arizona State (O/U 53) | 10:30 p.m. | ESPN | Arizona State, 34-24 (Arizona State, 28-10) |
| Thursday, October 7 | |||
| Matchup | Time | TV | Prediction |
| #11 Coastal Carolina (-19.5) at Arkansas State (O/U 73) | 7:30 p.m. | ESPNU | Coastal Carolina, 45-24 (Ciastak Carolina, 52-20) |
| Houston (-6.5) at Tulane (O/U 59.5) | 7:30 p.m. | ESPN | Houston, 38-27 (Houston, 40-22) |
