Record:
Last week: SU – 36-18; ATS – 23-28-1; O/U – 28-23-1
Overall: SU – 432-136; ATS – 227-229-9; O/U – 245-209-11
Upsets are bold underlined
(Results in parentheses; wins are underlined; losses in italics)
* – Picks with extreme confidence ATS
^ – Picks with low confidence ATS
| Tuesday, Nov. 1 | |||
| Matchup | Time (ET) | TV Coverage | Prediction (Result) |
| Bowling Green (+17) at NIU (O/U 72) | 8 p.m. | ESPNU | Northern Illinois, 41-17 (Northern Illinois, 45-20) |
| #7 Western Michigan (-17.5) at Ball State (O/U 64) | 8 p.m. | ESPN2 | Western Michigan, 42-21 (Western Michigan, 52-20) |
| Wednesday, Nov. 2 | |||
| Matchup | Time (ET) | TV Coverage | Prediction (Result) |
| Toledo (-10) at Akron (O/U 72) | 7:30 p.m. | ESPN2 | Toledo, 35-17 (Toledo, 48-17) |
| Thursday, Nov. 3 | |||
| Matchup | Time (ET) | TV Coverage | Prediction (Result) |
| Buffalo (+17.5) at Ohio (O/U 51.5) | 6 p.m. | CBSSN | Ohio, 41-17 (Ohio, 34-10) |
| Arkansas State (-4.5) at Georgia State (O/U 48) | 7:30 p.m. | ESPNU | Arkansas State, 27-14 (Arkansas State, 31-16) |
| #8 Oklahoma (-21) at Iowa State (O/U 71.5) | 7:30 p.m. | ESPN | Oklahoma, 41-21 (Oklahoma, 34-24) |
| UCLA (+13.5) at Colorado (O/U 57.5) | 9 p.m. | FS1 | Colorado, 34-17 (Colorado, 20-10) |
| Friday, Nov. 4 | |||
| Matchup | Time (ET) | TV Coverage | Prediction (Result) |
| Central Michigan (-3.5) at Miami (Ohio) (O/U 46.5) | 6 p.m. | CBSSN | Miami, 27-24 (Miami, 37-17) |
| Temple (-10) at Connecticut (O/U 45) | 7 p.m. | ESPN2 | Temple, 34-21 (Temple, 21-0) |
| San Jose State (+29.5) at #23 Boise State (O/U 57.5) | 10:15 p.m. | ESPN2 | Boise State, 48-17 (Boise State, 45-31) |
| Saturday, Nov. 5 | |||
| Matchup | Time (ET) | TV Coverage | Prediction (Result) |
| Navy (+6.5) vs. Notre Dame (at Jacksonville, Fla.) (O/U 64.5) | 11:30 a.m. | CBS | Notre Dame, 34-30 (Navy, 28-27) |
| Air Force (+1.5) at Army (O/U 47.5) | Noon | CBSSN | Army, 35-31 (Air Force, 31-12) |
| Georgia Southern (+27.5) at Ole Miss (O/U 63) | Noon | ESPNU | Ole Miss, 45-27 (Ole Miss, 37-27) |
| Indiana (-14) at Rutgers (O/U 58) | Noon | BTN | Indiana, 34-14 (Indiana, 33-27) |
| #5 Louisville (-25) at Boston College (O/U 55) | Noon | ESPN2 | Louisville, 48-20 (Louisville, 52-7) |
| Michigan State (-7) at Illinois (O/U 50) | Noon | ESPNews | Michigan State, 24-21 (lllinois, 31-27) |
| Texas (-3) at Texas Tech (O/U 81.5) | Noon | FS1 | Texas Tech, 45-41 (Texas, 45-37) |
| #15 Texas A&M (-11.5) at Mississippi State (O/U 62.5) | Noon | SECN | Texas A&M, 45-31 (Mississippi State, 35-28) |
| Vanderbilt (+26) at #10 Auburn (O/U 45) | Noon | ESPN | Auburn, 34-14 (Auburn, 23-16) |
| #13 Wisconsin (-6) at Northwestern (O/U 41) | Noon | ABC | Wisconsin, 21-17 (Wisconsin, 21-7) |
| Pittsburgh (+4) at Miami (Fla.) (O/U 58.5) | 12:30 p.m. | ACCN | Miami, 34-27 (Miami, 51-28) |
| Georgia Tech (+10) at #20 North Carolina (O/U 61.5) | 12:30 p.m. | ACCN | North Carolina, 38-31 (North Carolina, 48-20) |
| UTSA (+20) at Middle Tennessee (O/U 64.5) | 2:30 p.m. | ESPN3 | Middle Tennessee, 41-27 (UTSA, 45-20) |
| Virginia (+3) at Wake Forest (O/U 45) | 3 p.m. | RSN | Wake Forest, 27-23 (Wake Forest, 27-20) |
| BYU (-7.5) at Cincinnati (O/U 55) | 3:30 p.m. | CBSSN | BYU, 35-20 (BYU, 20-3) |
| Charlotte (+19.5) at Southern Miss (O/U 61.5) | 3:30 p.m. | ASN | Southern Miss, 37-24 (Charlotte, 38-27) |
| #9 Florida (-3.5) at Arkansas (O/U 46.5) | 3:30 p.m. | CBS | Florida, 24-14 (Arkansas, 31-10) |
| Florida Atlantic (+4) at Rice (O/U 57.5) | 3:30 p.m. | ESPN3 | Rice, 27-21 (FAU, 42-25) |
| Fresno State (+15.5) at Colorado State (O/U 53.5) | 3:30 p.m. | ROOT SPORTS | Colorado State, 38-21 (Colorado State, 37-0) |
| Maryland (+30.5) at #3 Michigan (O/U 54) | 3:30 p.m. | ESPN | Michigan, 38-14 (Michigan, 59-3) |
| #11 Oklahoma State (+3) at Kansas State (O/U 56) | 3:30 p.m. | ABC/ESPN2 | Oklahoma State, 38-31 (Oklahoma State, 43-27) |
| Oregon State (+15.5) at Stanford (O/U 42.5) | 3:30 p.m. | FS1 | Stanford, 27-14 (Stanford, 26-15) |
| Purdue (+17.5) at Minnesota (O/U 56.5) | 3:30 p.m. | BTN | Minnesota, 41-17 (Minnesota, 44-31) |
| Syracuse (+26.5) at #2 Clemson (O/U 68) | 3:30 p.m. | ABC/ESPN2 | Clemson, 45-17 (Clemson, 54-0) |
| TCU (+7.5) at #24 Baylor (O/U 68.5) | 3:30 p.m. | FOX | Baylor, 35-24 (TCU, 62-22) |
| Texas State (+31) at Appalachian State (O/U 54) | 3:30 p.m. | ESPN3 | Appalachian State, 45-17 (Appalachian State, 35-10) |
| Massachusetts (+21) at Troy (O/U 56.5) | 3:30 p.m. | ESPN3 | Troy, 37-17 (Troy, 52-31) |
| #19 Virginia Tech (-11) at Duke (O/U 54.5) | 3:30 p.m. | ESPNU | Virginia Tech, 34-20 (Virginia Tech, 24-21) |
| Arizona (+16.5) at #21 Washington State (O/U 65.5) | 4 p.m. | Pac-12N | Washington State, 44-21 (Washington, 69-7) |
| Memphis (-3) at SMU (O/U 65) | 4 p.m. | ESPNews | SMU, 34-30 (Memphis, 51-7) |
| Missouri (+6.5) at South Carolina (O/U 56) | 4 p.m. | SECN | South Carolina, 24-17 (South Carolina, 31-21) |
| Tennessee Tech (NL) at #25 Tennessee | 4 p.m. | SECN Alt. | Tennessee, 48-14 (Tennessee, 55-0) |
| Idaho (+5) at Louisiana-Lafayette (O/U 55) | 5 p.m. | ESPN3 | Louisiana-Lafayette, 34-27 (Idaho, 23-13) |
| South Alabama (-12.5) at ULM (O/U 50.5) | 5 p.m. | ESPN3 | South Alabama, 34-17 (ULM, 42-35) |
| Tulane (+16.5) at UCF (O/U 49.5) | 5 p.m. | ESPN3 | UCF, 44-24 (UCF, 37-6) |
| FIU (+32.5) at Western Kentucky (O/U 64.5) | 5:30 p.m. | beIN Sports | Western Kentucky, 49-10 (Western Kentucky, 49-21) |
| Louisiana Tech (-20) at North Texas (O/U 65.5) | 5:30 p.m. | ESPN3 | Louisiana Tech, 34-21 (Louisiana Tech, 45-24) |
| #18 Florida State (-6) at NC State (O/U 58) | 7 p.m. | ESPNU | Florida State, 24-17 (Florida State, 24-20) |
| Hawaii (+21.5) at San Diego State (O/U 53.5) | 7 p.m. | CBSSN | San Diego State, 37-20 (San Diego State, 55-0) |
| Kansas (+34.5) at #16 West Virginia (O/U 54) | 7 p.m. | ESPN2 | West Virginia, 54-14 (West Virginia, 48-21) |
| Marshall (+11) at Old Dominion (O/U 58) | 7 p.m. | ASN | Old Dominion, 34-20 (Old Dominion, 38-14) |
| Oregon (+17) at #22 USC (O/U 78.5) | 7 p.m. | ESPN | USC, 41-27 (USC, 45-20) |
| Georgia (-2) at Kentucky (O/U 51.5) | 7:30 p.m. | SECN | Kentucky, 27-21 (Georgia, 27-24) |
| Iowa (+6.5) at #17 Penn State (O/U 52.5) | 7:30 p.m. | BTN | Penn State, 21-14 (Penn State, 41-14) |
| #1 Alabama (-7.5) at #12 LSU (O/U 45) | 8 p.m. | CBS | Alabama, 34-17 (Alabama, 10-0) |
| East Carolina (+10) at Tulsa (O/U 75) | 8 p.m. | ESPNews | Tulsa, 48-27 (Tulsa, 45-24) |
| Houston Baptist (NL) at UTEP | 8 p.m. | CUSA.TV | UTEP, 34-24 (UTEP, 42-10) |
| #14 Nebraska (+17) at #6 Ohio State (O/U 52.5) | 8 p.m. | ABC | Ohio State, 31-20 (Ohio State, 62-3) |
| Nevada (+15) at New Mexico (O/U 59.5) | 10:15 p.m. | ESPNU | New Mexico, 28-21 (New Mexico, 35-26) |
| Utah State (+4.5) at Wyoming (O/U 55.5) | 10:15 p.m. | ESPN2 | Wyoming, 31-21 (Wyoming, 52-28) |
| #4 Washington (-18) at California (O/U 76.5) | 10:30 p.m. | ESPN | Washington, 56-24 (Washington, 66-27) |
