Record:
This week: SU – 38-16; ATS – 27-25-1; O/U – 22-30-1
Overall: SU – 323-92; ATS – 184-200-4; O/U – 180-201-7
(Results in parentheses)
| Saturday, October 23 | |||
| Matchup | Time | TV | Prediction |
| UMass (+35.5) at Florida State (O/U 60) | Noon | ACCN | Florida State, 45-17 (Florida State, 59-3) |
| #3 Oklahoma (-38.5) at Kansas (O/U 66.5) | Noon | ESPN | Oklahoma, 58-14 (Oklahoma, 35-23) |
| Northwestern (+23.5) at #5 Michigan (O/U 50.5) | Noon | FOX | Michigan, 34-17 (Michigan, 33-7) |
| Illinois (+24) at #11 Penn State (O/U 46.5) | Noon | ABC | Penn State, 23-7 (Illinois, 20-18 9OT) |
| Eastern Michigan (-3) at Bowling Green (O/U 49) | Noon | ESPN+ | Bowling Green, 28-27 (Eastern Michigan, 55-24) |
| Northern Illinois (+5) at Central Michigan (O/U 57.5) | Noon | ESPNU | Northern Illinois, 31-24 (Northern Illnois, 39-38) |
| Arkansas Pine-Bluff (NL) at Arkansas | Noon | SECN | Arkansas, 58-7 (Arkansas, 45-3) |
| Kansas State (+1) at Texas Tech (O/U 60.5) | Noon | FS1 | Texas Tech, 35-31 (Kansas State, 25-24) |
| #13 Wake Forest (-3) at Army (O/U 52.5) | Noon | CBSSN | Wake Forest, 31-24 (Wake Forest, 70-56) |
| #2 Cincinnati (-27.5) at Navy (O/U 48.5) | Noon | ESPN2 | Cincinnati, 34-17 (Cincinnati, 27-20) |
| Syracuse (+3) at Virginia Tech (O/U 45.5) | 12:30 p.m. | CSS | Syracuse, 24-21 (Syracuse, 41-36) |
| Kent State (-5.5) at Ohio (O/U 66.5) | 1 p.m. | ESPN+ | Kent State, 34-28 (Kent State, 34-27) |
| Texas State (+10.5) at Georgia State (O/U 60.5) | 2 p.m. | ESPN+ | Georgia State, 34-31 (Georgia State, 28-16) |
| Wisconsin (-3) at Purdue (O/U 40) | 3 p.m. | BTN | Wisconsin, 21-14 (Wisconsin, 30-13) |
| #22 Clemson (+3) at #21 Pittsburgh (O/U 48) | 3:30 p.m. | ESPN | Pittsburgh, 27-17 (Pittsburgh, 27-17) |
| #9 Oklahoma State (+7) at Iowa State (O/U 47) | 3:30 p.m. | FOX | Iowa State, 31-28 (Iowa State, 24-21) |
| Maryland (+5) at Minnesota (O/U 55) | 3:30 p.m. | ESPN2 | Minnesota, 33-27 (Minnesota, 34-16) |
| Buffalo (-11) at Akron (O/U 57.5) | 3:30 p.m. | ESPN+ | Buffalo, 34-17 (Buffalo, 45-10) |
| Miami (Ohio) (+5) at Ball State (O/U 51.5) | 3:30 p.m. | ESPN+ | Miami, 41-31 (Miami, 24-17) |
| Western Michigan (-1.5) at Toledo (O/U 54.5) | 3:30 p.m. | CBSSN | Western Michigan, 27-21 (Toledo, 34-15) |
| Colorado (+8.5) at California (O/U 43) | 3:30 p.m. | P12N | California, 24-17 (California, 26-3) |
| #12 Oregon (+2) at UCLA (O/U 60.5) | 3:30 p.m. | ABC | UCLA, 27-23 (Oregon, 34-31) |
| BYU (-4.5) at Washington State (O/U 56) | 3:30 p.m. | FS1 | BYU, 31-28 (BYU, 21-19) |
| LSU (+9) at #20 Ole Miss (O/U 76) | 3:30 p.m. | CBS | Ole Miss, 45-38 (Ole Miss, 31-17) |
| New Mexico (+20) at Wyoming (O.U. 40.5) | 3:30 p.m. | STAD | Wyoming, 27-10 (New Mexico, 14-3) |
| Rice (+23) at UAB (O/U 45) | 3:30 p.m. | ESPN+ | UAB, 41-14 (Rice, 30-24) |
| Mississippi State (-20.5) at Vanderbilt (O/U 51) | 4 p.m. | SECN | Mississippi State, 35-17 (Mississippi State, 45-6) |
| East Carolina (+13) at Houston (O/U 58) | 4 p.m. | ESPNU | Houston, 38-17 (Houston, 31-24) |
| Boston College (+6) at Louisville (O/U 57) | 4 p.m. | ACCN | Louisville, 31-27 (Louisville, 28-14) |
| Liberty (-21.5) at North Texas (O/U 60.5) | 4 p.m. | ESPN+ | Liberty, 45-14 (Liberty, 35-26) |
| UTSA (-7) at Louisiana Tech (O/U 60) | 7 p.m. | STAD | UTSA, 31-28 (UTSA, 45-16) |
| Tennessee (+25) at #6 Alabama (O/U 67) | 7 p.m. | ESPN | Alabama, 45-17 (Alabama, 52-24) |
| #23 San Diego State (+3.5) at #25 Air Force (O/U 39) | 7 p.m. | CBSSN | Air Force, 24-21 (San Diego State, 20-14) |
| Nevada (+3) at Fresno State (O/U 65) | 7 p.m. | FS2 | Nevada, 30-24 (Fresno State, 34-32) |
| South Alabama (-13.5) at Louisiana-Monroe (O/U 51) | 7 p.m. | ESPN3 | South Alabama, 31-23 (Louisiana-Monroe, 41-31) |
| Temple (+2.5) at USF (O/U 55) | 7 p.m. | ESPN+ | USF, 30-27 (USF, 34-14) |
| Western Kentucky (-15) at FIU (O/U 77) | 7 p.m. | ESPN+ | Western Kentucky, 48-28 (Western Kentucky, 34-19) |
| Georgia Tech (+7) at Virginia (O/U 63.5) | 7:30 p.m. | ACCN | Virginia Tech, 34-24 (Virginia, 48-40) |
| #14 N.C. State (-3) at Miami (Fla.) (O/U 51.5) | 7:30 p.m. | ESPN2 | N.C. State 34-30 (Miami, 31-30) |
| #4 Ohio State (-21) at Indiana (O/U 60.5) | 7:30 p.m. | ABC | Ohio State, 41-13 (Ohio State, 54-7) |
| Utah (-3) at Oregon State (O/U 56.5) | 7:30 p.m. | P12N | Utah, 31-26 (Oregon State, 42-34) |
| South Carolina (+20.5) at #15 Texas A&< (O/U 45) | 7:30 p.m. | SECN | Texas A&M, 40-17 (Texas A&M, 44-14) |
| West Virginia (+4.5) at TCU (O.U 56.5) | 7:30 p.m. | ESPNU | TCU, 30-24 (West Virginia, 29-17) |
| USC (+6.5) at #7 Notre Dame (O/U 57.5) | 7:30 p.m. | NBC | Notre Dame, 31-23 (Notre Dame, 31-16) |
| New Mexico State (+18) at Hawaii (O/U 59.5) | Midnight | Team1 App | Hawaii, 27-14 (Hawaii, 48-34) |
| Friday, October 22 | |||
| Matchup | Time | TV | Prediction |
| Middle Tennessee (-15.5) at UConn (O/U 56) | 6 p.m. | CBSSN | Middle Tennessee, 31-17 (Middle Tennessee, 44-13) |
| Memphis (-1) at UCF (O/U 63.5) | 7 p.m. | ESPN2 | UCF, 35-31 (UCF, 24-7) |
| Colorado State (-3.5) at Utah State (O/U 58.5) | 9:30 p.m. | CBSSN | Colorado State, 31-24 (Utah State, 26-24) |
| Washington (-18) at Arizona (O/U 46.5) | 10:30 p.m. | ESPN2 | Washington, 31-10 (Washington, 21-16) |
| Thursday, October 21 | |||
| Matchup | Time | TV | Prediction |
| Louisiana (-18) at Arkansas State (O/U 70) | 7:30 p.m. | ESPNU | Louisiana, 44-24 (Louisiana, 28-27) |
| Tulane (+14) at #24 SMU (O.U 70.5) | 7:30 p.m. | ESPNU | SMU, 41-24 (SMU, 55-26) |
| FAU (-7) at Charlotte (O/U 57) | 7:30 p.m. | CBSSN | FAU, 28-24 (FAU, 38-9) |
| San Jose State (-3.5) at UNLV (O/U 44) | 11 p.m. | CBSSN | UNLV, 23-20 (San Jose State, 27-20) |
| Tuesday, October 19 | |||
| Matchup | Time | TV | Prediction |
| #10 Coastal Carolina (-4.5) at Appalachian State (O/U 60.5) | 7:30 p.m. | ESPN2 | Coastal Carolina, 35-28 (Appalachian State, 30-27) |
