Record:
This week: SU – 3-2; ATS – 1-4-0; O/U – 2-3-0
Overall: SU – 320-90; ATS – 158-179-3; O/U – 160-174-6
(Results in parentheses)
| Friday, October 22 | |||
| Matchup | Time | TV | Prediction |
| Middle Tennessee (-15.5) at UConn (O/U 56) | 6 p.m. | CBSSN | Middle Tennessee, 31-17 |
| Memphis (-1) at UCF (O/U 63.5) | 7 p.m. | ESPN2 | UCF, 35-31 |
| Colorado State (-3.5) at Utah State (O/U 58.5) | 9:30 p.m. | CBSSN | Colorado State, 31-24 |
| Washington (-18) at Arizona (O/U 46.5) | 10:30 p.m. | ESPN2 | Washington, 31-10 |
| Thursday, October 21 | |||
| Matchup | Time | TV | Prediction |
| Louisiana (-18) at Arkansas State (O/U 70) | 7:30 p.m. | ESPNU | Louisiana, 44-24 (Louisiana, 28-27) |
| Tulane (+14) at #24 SMU (O.U 70.5) | 7:30 p.m. | ESPNU | SMU, 41-24 (SMU, 55-26) |
| FAU (-7) at Charlotte (O/U 57) | 7:30 p.m. | CBSSN | FAU, 28-24 (FAU, 38-9) |
| San Jose State (-3.5) at UNLV (O/U 44) | 11 p.m. | CBSSN | UNLV, 23-20 (San Jose State, 27-20) |
| Tuesday, October 19 | |||
| Matchup | Time | TV | Prediction |
| #10 Coastal Carolina (-4.5) at Appalachian State (O/U 60.5) | 7:30 p.m. | ESPN2 | Coastal Carolina, 35-28 (Appalachian State, 30-27) |
