Record:
This week: SU – 45-17; ATS – 38-21-0; O/U – 26-31-2
Overall: SU – 481-152; ATS – 284-268-5; O/U – 258-289-10
(Results in parentheses)
| Saturday, November 6 | |||
| Matchup | Time | TV | Prediction |
| UConn (+42) at Clemson (O/U 51) | Noon | ACCN | Clemson, 38-0 (Clemson, 44-7) |
| #14 Houston (-24.5) at Temple (O/U 53) | Noon | ESPN+ | Houston, 44-17 (Houston, 37-8) |
| West Virginia (+6) at Kansas State (O/U 47) | Noon | FS1 | Kansas State, 27-23 (Kansas State, 34-17) |
| Rutgers (+7) at Indiana (O/U 42.5) | Noon | BTN | Indiana, 21-17 (Rutgers, 38-3) |
| #8 Michigan (-1.5) at #21 Penn State (O/U 48.5) | Noon | ABC | Michigan, 27-23 (Michigan, 21-17) |
| Northwestern (+24.5) at #18 Wisconsin (O/U 41) | Noon | ESPN2 | Wisconsin, 35-7 (Wisconsin, 35-7) |
| Samford (NL) at Florida | Noon | ESPN+ | Florida, 38-21 (Florida, 70-52) |
| New Mexico State (+51) at #5 Alabama (O/U 67) | Noon | SECN | Alabama, 51-7 (Alabama, 59-3) |
| Mississippi State (+5) at #22 Auburn (O/U 51) | Noon | ESPNU | Auburn, 27-23 (Mississippi State, 43-34) |
| #3 Oklahoma (-5.5) at Baylor (O/U 62.5) | Noon | FOX | Oklahoma, 38-24 (Baylor, 27-14) |
| UCF (+7) at SMU (O/U 61) | Noon | ESPNU | UCF, 27-21 (SMU, 55-28) |
| Bucknell (NL) at Army | Noon | CBSSN | Army, 45-14 (Army, 63-10) |
| Syracuse (+3) at Louisville (O/U 55.5) | Noon | CSS | Louisville, 31-27 (Louisville, 41-3) |
| East Carolina (+5) at Memphis (O/U 59) | Noon | ESPN+ | East Carolina, 34-24 (East Carolina, 30-29) |
| Maine (NL) at UMass | Noon | FLOF | Maine, 34-23 (Maine, 35-10) |
| Utah (-24) at Arizona (O/U 54) | 2 p.m. | P12N | Utah, 44-17 (Utah, 38-29) |
| Western Kentucky (-18.5) at Rice (O/U 61.5) | 2 p.m. | ESPN+ | Western Kentucky, 41-17 (Western Kentucky, 42-21) |
| Georgia State (+11) at #20 Coastal Carolina (O/U 52) | 2 p.m. | ESPN+ | Coastal Carolina, 31-17 (Georgia State, 42-40) |
| South Alabama (+22.5) at Appalachian State (O/U 52) | 2:30 p.m. | ESPN+ | Appalachian State, 41-24 (Appalachian State, 31-7) |
| Georgia Southern (+2) at Texas State (O/U 52.5) | 3 p.m. | ESPN+ | Texas State, 24-20 (Georgia Southern, 38-30) |
| Miami (Fla.) (-2.5) at Florida State (O/U 61) | 3:30 p.m. | ESPN | Miami, 34-31 (Florida State, 31-28) |
| Boston College (+1.5) at Georgia Tech (O/U 54.5) | 3:30 p.m. | CSS | Georgia Tech, 24-17 (Boston College, 41-30) |
| Duke (+11.5) at Virginia Tech (O/U 51) | 3:30 p.m. | ACCN | Virginia Tech, 27-14 (Virginia Tech, 48-17) |
| Minnesota (+4.5) at Iowa (O/U 37) | 3:30 p.m. | BTN | Minnesota, 17-14 (Iowa, 27-22) |
| #23 Purdue (+21) at #4 Ohio State (O/U 63.5) | 3:30 p.m. | ABC | Ohio State, 34-17 (Ohio State, 59-31) |
| Charlotte (+7) at Louisiana Tech (O/U 57) | 3:30 p.m. | STAD | Louisiana Tech, 31-23 (Louisiana Tech, 42-32) |
| #1 Georgia (-20) at Tennessee (O/U 56) | 3:30 p.m. | CBS | Georgia, 38-13 (Georgia, 41-17) |
| Iowa State (-10.5) at Texas Tech (O/U 57.5) | 3:30 p.m. | ESPN2 | Iowa State, 34-20 (Texas Tech, 41-38) |
| FIU (+10) at Middle Tennessee (O/U 55) | 3:30 p.m. | ESPN3 | Middle Tennessee, 31-20 (Middle Tennessee, 50-10) |
| UAB (+4.5) at Marshall (O/U 55.5) | 3:30 p.m. | CBSSN | Marshall, 31-27 (UAB, 21-14) |
| #19 Louisiana (-6.5) at Troy (O/U 48) | 3:30 p.m. | ESPN+ | Louisiana, 28-21 (Louisiana, 35-21) |
| FAU (-6.5) at Old Dominion (O/U 48.5) | 3:30 p.m. | ESPN+ | FAU, 34-30 (Old Dominion, 30-16) |
| Southern Miss (+33) at #16 UTSA (O/U 54.5) | 3:30 p.m. | ESPN+ | UTSA, 47-14 (UTSA, 27-17) |
| South Carolina (-1) at Missouri (O/U 55) | 4 p.m. | SECN | Missouri, 24-20 (Missouri, 31-28) |
| Maryland (+12) at #12 Michigan State (O/U 61.5) | 4 p.m. | FOX | Michigan State, 34-21 (Michigan State, 40-21) |
| Hawaii (-3.5) at UNLV (O/U 56) | 4 p.m. | PPV | UNLV, 28-24 (UNLV, 27-13) |
| Tulsa (-3) at Tulane (O/U 55.5) | 4 p.m. | ESPNU | Tulane, 23-21 (Tulsa, 20-13) |
| UTEP (-1) at North Texas (O/U 55) | 4 p.m. | ESPN+ | North Texas, 31-28 (North Texas, 20-17) |
| Arkansas State (+3) at Louisiana-Monroe (O/U 66.5) | 5 p.m. | ESPN+ | Louisiana-Monroe, 34-27 (Arkansas State, 27-24) |
| Stanford (+12.5) at Oregon State (O/U 56) | 5:30 p.m. | P12N | Oregon State, 35-24 (Oregon State, 35-14) |
| Arizona State (-5.5) at Washington (O/U 45.5) | 7 p.m. | FS1 | Arizona State, 31-21 (Arizona State, 35-30) |
| Kentucky (-21.5) at Vanderbilt (O/U 52.5) | 7 p.m. | ESPN2 | Kentucky, 38-17 (Kentucky, 34-17) |
| #9 Texas A&M (-2.5) at #11 Ole Miss (O/U 57) | 7 p.m. | ESPN | Texas A&M, 27-24 (Ole Miss, 29-19) |
| Air Force (-2.5) at Colorado State (O/U 45) | 7 p.m. | CBSSN | Air Force, 27-20 (Air Force, 35-21) |
| New Mexico (+24.5) at Fresno State (O/U 51) | 7 p.m. | STAD | Fresno State, 38-10 (Fresno State, 34-7) |
| #6 Notre Dame (-6.5) at Virginia (O/U 63) | 7:30 p.m. | ABC | Notre Dame, 34-24 (Notre Dame, 28-3) |
| #25 N.C. State (+2) at #17 Wake Forest (O/U 65.5) | 7:30 p.m. | ACCN | N.C. State, 38-35 (Wake Forest, 45-42) |
| Arkansas (-2.5) at LSU (O/U 59) | 7:30 p.m. | SECN | Arkansas, 31-24 (Arkansas, 16-13) |
| Kansas (+31) at Texas (O/U 62) | 7:30 p.m. | ESPNU | Texas, 48-24 (Kansas, 57-56 OT) |
| TCU (+12) at #10 Oklahoma State (O/U 54.5) | 8 p.m. | FOX | Oklahoma State, 34-21 (Oklahoma State, 63-17) |
| Colorado (+17.5) at UCLA (O/U 57) | 9 p.m. | P12N | UCLA, 41-23 (UCLA, 44-20) |
| Utah State (+4.5) at San Jose State (O/U 57.5) | 10:30 p.m. | FS1 | Utah State, 27-24 (Utah State, 48-17) |
| Washington State (+14) at #7 Oregon (O/U 57.5) | 10:30 p.m. | ESPN | Oregon, 27-24 (Oregon, 38-24) |
| Nevada (+3) at #24 San Diego State (O/U 45.5) | 10:30 p.m. | CBSSN | Nevada, 24-23 (San Diego State, 23-21) |
| Friday, November 5 | |||
| Matchup | Time | TV | Prediction |
| #2 Cincinnati (-23.5) at USF (O/U 58) | 6 p.m. | ESPN2 | Cincinnati, 41-20 (Cincinnati, 45-28) |
| Wyoming (+14) at Boise State (O/U 48.5) | 9 p.m. | FS1 | Boise State, 34-17 (Boise State, 23-13) |
| Thursday, November 4 | |||
| Matchup | Time | TV | Prediction |
| North Carolina (+6.5) at #13 Pittsburgh (O/U 71.5) | 7:30 p.m. | ESPN | Pittsburgh, 34-27 (Pittsburgh, 30-23) |
| Wednesday, November 3 | |||
| Matchup | Time | TV | Prediction |
| Ball State (-2.5) at Northern Illinois (O/U 59.5) | 7 p.m. | ESPN2 | Northern Illinois, 33-30 (Northern Illinois, 30-29) |
| Toledo (-10.5) at Bowling Green (O/U 50) | 7 p.m. | CBSSN | Toledo, 41-27 (Toledo, 49-17) |
| Kent State (+2.5) at Central Michigan (O/U 76.5) | 8 p.m. | ESPNU | Central Michigan, 38-34 (Central Michigan, 54-30) |
| Tuesday, November 2 | |||
| Matchup | Time | TV | Prediction |
| Buffalo (+7) at Miami (Ohio) (O/U 57.5) | 7 p.m. | ESPNU | Miami, 34-28 (Miami, 45-18) |
| Akron (+24.5) at Western Michigan (O/U 52) | 7 p.m. | CBSSN | Western Michigan, 27-20 (Western Michigan, 45-40) |
| Ohio (+6.5) at Eastern Michigan (O/U 62.5) | 8 p.m. | ESPN2 | Eastern Michigan, 31-24 (Ohio, 34-26) |
